Fabrication of ultrathin Zn(OH)2 nanosheets as drug carriers
aptamer, porous Zn(OH)2 nanosheets, cancer cell, cell-targeted delivery
Ultrathin two-dimensional (2D) porous Zn(OH)2 nanosheets (PNs) were fabricatedby means of one-dimensional Cu nanowires as backbones. The PNs have thicknessof approximately 3.8 nm and pore size of 4–10 nm. To form “smart” porousnanosheets, DNA aptamers were covalently conjugated to the surface of PNs.These ultrathin nanosheets show good biocompatibility, efficient cellular uptake,and promising pH-stimulated drug release.
Tsinghua University Press
Ren Cai,Dan Yang,Jin Wu,Liqin Zhang,Cuichen Wu,Xigao Chen,Yanyue Wang,Shuo Wan,Fengwei Hou,Qingyu Yan,Weihong Tan, Fabrication of ultrathin Zn(OH)2 nanosheets as drug carriers. NanoRes.2016, 9(8): 2520–2530