Article Title

Highly stable organic fluorescent nanorods for living-cell imaging

Authors

Minhuan Lan, Center of Super-Diamond and Advanced Films (COSDAF), Department of Physics and Materials Science, City University of Hong Kong, Hong Kong SAR, China
Jinfeng Zhang, Center of Super-Diamond and Advanced Films (COSDAF), Department of Physics and Materials Science, City University of Hong Kong, Hong Kong SAR, China
Xiaoyue Zhu, Center of Super-Diamond and Advanced Films (COSDAF), Department of Physics and Materials Science, City University of Hong Kong, Hong Kong SAR, China
Pengfei Wang, Key Laboratory of Photochemical Conversion and Optoelectronic Materials, Technical Institute of Physics and Chemistry (TIPC), Chinese Academy of Sciences (CAS), Beijing 100190, China
Xianfeng Chen, Center of Super-Diamond and Advanced Films (COSDAF), Department of Physics and Materials Science, City University of Hong Kong, Hong Kong SAR, China
Chun-Sing Lee, Center of Super-Diamond and Advanced Films (COSDAF), Department of Physics and Materials Science, City University of Hong Kong, Hong Kong SAR, China
Wenjun Zhang, Center of Super-Diamond and Advanced Films (COSDAF), Department of Physics and Materials Science, City University of Hong Kong, Hong Kong SAR, China

Keywords

cell imaging, organic dye, fluorescent nanorods, DPP

Abstract

Metal-free, organic-dye-based fluorescent nanorods were fabricated through a simple solvent-exchange procedure. The as-prepared nanorods exhibit low toxicity to living cells and excellent photostability. Furthermore, they are stable in solutions of various pHs and high ionic strength and in solutions with interfering metal ions. Compared with the free DPP-Br molecules in THF, these nanorods exhibit larger Stokes shift, broader absorption spectra, and greatly improved photostability. We successfully demonstrated the application of the nanorods, including their aforementioned beneficial characteristics, as a good fluorescence probe for bio-imaging.

Graphical Abstract

DOI

https://doi.org/10.1007/s12274-015-0748-4

Publisher

Tsinghua University Press

Recommended Citation

Minhuan Lan,Jinfeng Zhang,Xiaoyue Zhu,Pengfei Wang,Xianfeng Chen,Chun-Sing Lee,Wenjun Zhang, Highly stable organic fluorescent nanorods for living-cell imaging. NanoRes.2015, 8(7): 2380–2389