Article Title

Redox-sensitive colorimetric polyaniline nanoprobes synthesized by a solvent-shift process

Authors

Jihye Choi, Department of Chemical and Biomolecular Engineering, Yonsei University, Seoul 120-749, Republic of Korea
Yoochan Hong, Department of Biomedical Engineering, Yonsei University, Wonju 220-710, Republic of Korea
Eugene Lee, Department of Radiology, College of Medicine, Yonsei University, Seoul 120-752, Republic of Korea
Myeong-Hoon Kim, Department of Chemical and Biomolecular Engineering, Yonsei University, Seoul 120-749, Republic of Korea
Dae Sung Yoon, Department of Biomedical Engineering, Yonsei University, Wonju 220-710, Republic of Korea
Jinsuck Suh, Department of Radiology, College of Medicine, Yonsei University, Seoul 120-752, Republic of Korea YUHS-KRIBB Medical Convergence Research Institute, Seoul 120-752, Republic of Korea Severance Biomedical Science Institute (SBSI), Seoul 120-752, Republic of Korea
Yongmin Huh, Department of Radiology, College of Medicine, Yonsei University, Seoul 120-752, Republic of Korea YUHS-KRIBB Medical Convergence Research Institute, Seoul 120-752, Republic of Korea Severance Biomedical Science Institute (SBSI), Seoul 120-752, Republic of Korea
Seungjoo Haam, Department of Chemical and Biomolecular Engineering, Yonsei University, Seoul 120-749, Republic of Korea YUHS-KRIBB Medical Convergence Research Institute, Seoul 120-752, Republic of Korea
Jaemoon Yang, Department of Radiology, College of Medicine, Yonsei University, Seoul 120-752, Republic of Korea YUHS-KRIBB Medical Convergence Research Institute, Seoul 120-752, Republic of Korea Severance Integrative Research Institute for Cerebral and Cardiovascular Diseases, Yonsei University Health System, Seoul 120-752, Republic of Korea

Keywords

polyaniline, solvent-shifting, cancer, colorimetric, nanoprobe

Abstract

We have synthesized water-stable polyaniline nanoparticles coated with triarmed polyethylene glycol chains using a solvent-shift method and confirmed their colloidal size and aqueous solubility. Furthermore, we have demonstrated that the polyaniline nanoparticles can be doped with biological dopants to produce distinct color changes allowing the detection of live cancer cells.

Graphical Abstract

DOI

https://doi.org/10.1007/s12274-013-0312-z

Publisher

Tsinghua University Press

Recommended Citation

Jihye Choi,Yoochan Hong,Eugene Lee,Myeong-Hoon Kim,Dae Sung Yoon,Jinsuck Suh,Yongmin Huh,Seungjoo Haam,Jaemoon Yang, Redox-sensitive colorimetric polyaniline nanoprobes synthesized by a solvent-shift process. NanoRes.2013, 6(5): 356–364