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Nano Research

Article Title

Size-dependent joule heating of gold nanoparticles using capacitively coupled radiofrequency fields

Authors

Christine H. Moran, Department of Bioengineering, Rice University, 6100 Main Street, Houston, TX 7005, USA Department of Surgical Oncology, MD Anderson Cancer Center, 1515 Holcombe Blvd, Box 107, Houston, TX 77030, USA
Sean M. Wainerdi, Department of Surgical Oncology, MD Anderson Cancer Center, 1515 Holcombe Blvd, Box 107, Houston, TX 77030, USA Department of Bioengineering, Texas A&M University, College Station, TX 77843, USA
Tonya K. Cherukuri, Department of Chemistry and Richard E. Smalley Institute for Nanoscale Science and Technology, Rice University, 6100 Main Street, Houston, TX 77005, USA
Carter Kittrell, Department of Chemistry and Richard E. Smalley Institute for Nanoscale Science and Technology, Rice University, 6100 Main Street, Houston, TX 77005, USA
Benjamin J. Wiley, Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, MA 02138, USA
Nolan W. Nicholas, Department of Physics and Richard E. Smalley Institute for Nanoscale Science and Technology, Rice University, 6100 Main Street, Houston, TX 77005, USA
Steven A. Curley, Department of Surgical Oncology, MD Anderson Cancer Center, 1515 Holcombe Blvd, Box 107, Houston, TX 77030, USA Department of Mechanical Engineering and Material Science, Rice University, 6100 Main Street, Houston, TX 77005, USA
John S. Kanzius, Department of Bioengineering, Rice University, 6100 Main Street, Houston, TX 7005, USA Department of Surgical Oncology, MD Anderson Cancer Center, 1515 Holcombe Blvd, Box 107, Houston, TX 77030, USA Department of Bioengineering, Texas A&M University, College Station, TX 77843, USA Department of Chemistry and Richard E. Smalley Institute for Nanoscale Science and Technology, Rice University, 6100 Main Street, Houston, TX 77005, USA Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, MA 02138, USA Department of Physics and Richard E. Smalley Institute for Nanoscale Science and Technology, Rice University, 6100 Main Street, Houston, TX 77005, USA Department of Mechanical Engineering and Material Science, Rice University, 6100 Main Street, Houston, TX 77005, USA Department of Experimental Therapeutics, MD Anderson Cancer Center, 1515 Holcombe Blvd, Box 107, Houston, TX77030, USA
Paul Cherukuri, Department of Surgical Oncology, MD Anderson Cancer Center, 1515 Holcombe Blvd, Box 107, Houston, TX 77030, USA Department of Chemistry and Richard E. Smalley Institute for Nanoscale Science and Technology, Rice University, 6100 Main Street, Houston, TX 77005, USA Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, MA 02138, USA Department of Experimental Therapeutics, MD Anderson Cancer Center, 1515 Holcombe Blvd, Box 107, Houston, TX77030, USA

Keywords

Resistivity, radiofrequency, gold, nanoparticles, cancer, thermal

Abstract

Capacitively coupled shortwave radiofrequency fields (13.56 MHz) resistively heat low concentrations (~1 ppm) of gold nanoparticles with a thermal power dissipation of ~380 kW/g of gold. Smaller diameter gold nanoparticles (< 50 nm) heat at nearly twice the rate of larger diameter gold nanoparticles (≥50 nm), which is attributed to the higher resistivity of smaller gold nanostructures. A Joule heating model has been developed to explain this phenomenon and provides critical insights into the rational design and engineering of nanoscale materials for noninvasive thermal therapy of cancer.

Graphical Abstract

Publisher

Tsinghua University Press

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