Article Title

Biomolecule-templated photochemical synthesis of silver nanoparticles: Multiple readouts of localized surface plasmon resonance for pattern recognition

Authors

Fang Pu, Laboratory of Chemical Biology and State Key Laboratory of Rare Earth Resources Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China
Xiang Ran, Laboratory of Chemical Biology and State Key Laboratory of Rare Earth Resources Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China University of Chinese Academy of Sciences, Beijing 100039, China
Meng Guan, Cancer Center, First Affiliated Hospital, Jilin University, Changchun 130061, China
Yanyan Huang, Laboratory of Chemical Biology and State Key Laboratory of Rare Earth Resources Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China University of Chinese Academy of Sciences, Beijing 100039, China
Jinsong Ren, Laboratory of Chemical Biology and State Key Laboratory of Rare Earth Resources Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China
Xiaogang Qu, Laboratory of Chemical Biology and State Key Laboratory of Rare Earth Resources Utilization, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022, China

Keywords

localized surface plasmon resonance, silver nanoparticles, pattern recognition, biomolecule, photochemical synthesis

Abstract

ABSTRACT Silver nanoparticles (AgNPs) with distinct localized surface plasmon resonance (LSPR) absorption spectra can be synthesized using different proteins as templates upon irradiation by light. We utilized the multiple readouts of LSPR signals of AgNPs to construct sensor arrays for pattern recognition of proteins. Room temperature, aqueous solutions, and lack of harsh reducing reagents make the whole process inherently ‘‘green’’. Meanwhile, the strategy efficiently simplified the process of array-receptor preparation and data acquisition, leading to lower time consumption, sample use, and cost. Furthermore, the system can differentiate proteins using flexible and alterable sensor elements by choosing different combinations of LSPR signals at different wavelengths. The principle of the sensor design can also be further extended to differentiate other biomolecules. The study provides a new method to construct feasible, economical, and general nanoparticle-based sensing arrays for pattern recognition.

Graphical Abstract

DOI

https://doi.org/10.1007/s12274-017-1819-5

Publisher

Tsinghua University Press

Recommended Citation

Fang Pu,Xiang Ran,Meng Guan,Yanyan Huang,Jinsong Ren,Xiaogang Qu, Biomolecule-templated photochemical synthesis of silver nanoparticles: Multiple readouts of localized surface plasmon resonance for pattern recognition. NanoRes.2018, 11(6): 3213–3221