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Journal of Neurorestoratology

Authors

Hongyun Huang, Beijing Hongtianji Neuroscience Academy, Beijing 100143, China
Lin Chen, Department of Neurosurgery, Dongzhimen Hospital, Beijing University of Traditional Chinese Medicine Beijing, Beijing 100007, China
Michael Chopp, Department of Neurology, Henry Ford Hospital, Detroit, MI, USA;Department of Physics, Oakland University, Rochester, MI, USA
Wise Young, Department of Cell Biochemistry and Neuroscience, Rutgers University, New Jersey, USA
John Robert Bach, Center for Ventilator Management Alternatives, University Hospital, Newark, New Jersey, USA
Xijing He, Department of Orthopedics, The Second Affiliated Hospital of Xi’an Jiaotong University, Xi’an 710004, Shaanxi, China
Anna Sarnowaska, Translational Platform for Regenerative Medicine & Cell Therapy Team of The Central Nervous System Diseases, Polish Academy of Sciences, Warsaw, Poland
Mengzhou Xue, The Department of Cerebrovascular Diseases, The Second Affiliated Hospital of Zhengzhou University, Henan Joint International Laboratory of Intracerebral Hemorrhagic Brain Injury, Zhengzhou 450001, Henan, China
Robert Chunhua Zhao, Center of Excellence in Tissue Engineering, Institute of Basic Medical Sciences and School of Basic Medicine, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing Key Laboratory of New Drug Development and Clinical Trial of Stem Cell Therapy, Beijing 100005, China
Ashok Shetty, Institute for Regenerative Medicine, Department of Molecular and Cellular Medicine, College of Medicine, Texas A&M University, USA
Dario Siniscalco, Department of Experimental Medicine, University of Campania "Luigi Vanvitelli" via S. Maria di Costantinopoli 16 80138Naples, Italy
Xiaoling Guo, Neurological Center, The 981 Hospital of PLA, Chengde 067000, Hebei, China
Alireza Khoshnevisan, School of Medicine, The University of Jordan, Amman, Jordan
Ziad Hawamdeh, Department of Neurosurgery, Tehran University of Medical Sciences, Tehran, Iran

Keywords

Neurorestoratology, yearbook, pathogenesis, neurorestorative mechanism, therapeutic achievement, guidelines, standards

Abstract

COVID-19 has been an emerging and rapidly evolving risk to people of the world in 2020. Facing this dangerous situation, many colleagues in Neurorestoratology did their best to avoid infection if themselves and their patients, and continued their work in the research areas described in the 2020 Yearbook of Neurorestoratology. Neurorestorative achievements and progress during 2020 includes recent findings on the pathogenesis of neurological diseases, neurorestorative mechanisms and clinical therapeutic achievements. Therapeutic progress during this year included advances in cell therapies, neurostimulation/neuromodulation, brain-computer interface (BCI), and pharmaceutical neurorestorative therapies, which improved neurological functions and quality of life for patients. Four clinical guidelines or standards of Neurorestoratology were published in 2020. Milestone examples include: 1) a multicenter randomized, double-blind, placebo-controlled study of olfactory ensheathing cell treatment of chronic stroke showed functional improvements; 2) patients after transhumeral amputation experienced increased sensory acuity and had improved effectiveness in work and other activities of daily life using a prosthesis; 3) a patient with amyotrophic lateral sclerosis used a steady-state visual evoked potential (SSVEP)-based BCI to achieve accurate and speedy computer input; 4) a patient with complete chronic spinal cord injury recovered both motor function and touch sensation with a BCI and restored ability to detect objects by touch and several sensorimotor functions. We hope these achievements motivate and encourage other scientists and physicians to increase neurorestorative research and its therapeutic applications.

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