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Journal of Advanced Ceramics

Authors

Ming-Zhu PAN, State Key Laboratory of Materials Processing and Die & Mould Technology, School of Materials Science and Engineering, Huazhong University of Science and Technology, Wuhan 430074, China;Engineering Research Center of Ceramic Materials for Additive Manufacturing, Ministry of Education, Wuhan 430074, China
Shuai-Bin HUA, State Key Laboratory of Materials Processing and Die & Mould Technology, School of Materials Science and Engineering, Huazhong University of Science and Technology, Wuhan 430074, China;Engineering Research Center of Ceramic Materials for Additive Manufacturing, Ministry of Education, Wuhan 430074, China
Jia-Min WU, State Key Laboratory of Materials Processing and Die & Mould Technology, School of Materials Science and Engineering, Huazhong University of Science and Technology, Wuhan 430074, China;Engineering Research Center of Ceramic Materials for Additive Manufacturing, Ministry of Education, Wuhan 430074, China
Xi YUAN, Department of Orthopedic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
Ze-Lin DENG, State Key Laboratory of Materials Processing and Die & Mould Technology, School of Materials Science and Engineering, Huazhong University of Science and Technology, Wuhan 430074, China;Engineering Research Center of Ceramic Materials for Additive Manufacturing, Ministry of Education, Wuhan 430074, China
Jun XIAO, Department of Orthopedic Surgery, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China
Yu-Sheng SHI, State Key Laboratory of Materials Processing and Die & Mould Technology, School of Materials Science and Engineering, Huazhong University of Science and Technology, Wuhan 430074, China;Engineering Research Center of Ceramic Materials for Additive Manufacturing, Ministry of Education, Wuhan 430074, China

Keywords

biphasic calcium phosphate (BCP), T-ZnOw, digital light processing (DLP), double-layer structure, cure property, mechanical strength

Abstract

Bone scaffolds require both good bioactivity and mechanical properties to keep shape and promote bone repair. In this work, T-ZnOw enhanced biphasic calcium phosphate (BCP) scaffolds with triply periodic minimal surface (TPMS)-based double-layer porous structure were fabricated by digital light processing (DLP) with high precision. Property of suspension was first discussed to obtain better printing quality. After sintering, T-ZnOw reacts with β-tricalcium phosphate (β-TCP) to form Ca19Zn2(PO4)14, and inhibits the phase transition to α-TCP. With the content of T-ZnOw increasing from 0 to 2 wt%, the flexural strength increases from 40.9 to 68.5 MPa because the four-needle whiskers can disperse stress, and have the effect of pulling out as well as fracture toughening. However, excessive whiskers will reduce the cure depth, and cause more printing defects, thus reducing the mechanical strength. Besides, T-ZnOw accelerates the deposition of apatite, and the sample with 2 wt% T-ZnOw shows the fastest mineralization rate. The good biocompatibility has been proved by cell proliferation test. Results confirmed that doping T-ZnOw can improve the mechanical strength of BCP scaffolds, and keep good biological property, which provides a new strategy for better bone repair.

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