"A review on the ongoing quest for a pain signature in the human brain" by Qian Su, Yingchao Song et al.

Article Title

A review on the ongoing quest for a pain signature in the human brain

Authors

Qian Su, Department of Molecular Imaging and Nuclear Medicine, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin Key Laboratory of Cancer Prevention and Therapy, Tianjin's Clinical Research Center for China, Tianjin 300060, China
Yingchao Song, School of Medical Imaging and Tianjin Key Laboratory of Functional Imaging, Tianjin Medical University, Tianjin 300070, China
Rui Zhao, Department of Orthopedics Surgery, Tianjin Medical University General Hospital, Tianjin 300052, China
Meng Liang, School of Medical Imaging and Tianjin Key Laboratory of Functional Imaging, Tianjin Medical University, Tianjin 300070, China

Keywords

pain signature, neuroimaging, machine learning, saliency, MVPA, specificity

Abstract

Developing an objective biomarker for pain assessment is crucial for understanding neural coding mechanisms of pain in the human brain as well as for effective treatment of pain disorders. Neuroimaging techniques have been proven to be powerful tools in the ongoing quest for a pain signature in the human brain. Although there is still a long way to go before achieving a truly successful pain signature based on neuroimaging techniques, important progresses have been made through great efforts in the last two decades by the Pain Society. Here, we focus on neural responses to transient painful stimuli in healthy people, and review the relevant studies on the identification of a neuroimaging signature for pain.

DOI

https://doi.org/10.26599/BSA.2019.9050024

Publisher

Tsinghua University Press

Recommended Citation

Qian Su, Yingchao Song, Rui Zhao et al. A review on the ongoing quest for a pain signature in the human brain. Brain Science Advances 2019, 05(04): 274-287.

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